It's all hands on deck when a tremendous explosion sends dozens of casualties to San Antonio Memorial Hospital. Topher leads the team while Jordan, Ragosa and Krista treat the traumatized patients and their families. TC, Drew, and Gwen race to the scene of the downtown explosion, where they accept the help of a Good Samaritan and former Army Medic, Bennett. Amidst the chaos, Paul tackles his first night in surgery rotation but gets an unwelcome surprise when his father, renowned neurosurgeon Julian Cummings unexpectedly arrives and butts heads with lead surgeon Scott.